Midazolam & Seizures - Essay ExampleMidozolam increases the activity of GABA which gives a calming effect to the user. It also relaxes the skeletal muscles and result in sleep. The chemical in the medicine called benzodiazepines bind to the receptors of GABA which enhances the effect of GABA by increasing the frequency of chloride channel opening.According to (Silver,1994,pg 350-60) “Midazolam is a potent imidazobenzodiazepine used as a premedicant and as an anesthetic induction Agent”.Midazolam is likely an agonist at both BZ1 and BZ2 receptors. Its performance at PBRs is not certain. The quick encephalopathic effects ofmidazolam may be connected to the trizolam like potency and lipophilicity of midazolam. Which are greatest among thebenzodizepines. Midazolam may also exert some anticholinergic activity.Silver, T, 1994. SCIENTIFIC ARTICLE Evaluation of two dosages of oral midazolam as a conscious sedation for physically and neurologically compromised pediatric dental patients.

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